When leaving an ISO 7 area, which item does not require changing?

In an ISO 7 area, maintaining a sterile environment is crucial for preventing contamination, especially when handling sterile products. Each item worn by personnel serves a specific purpose in contamination prevention.

The gown is designed to cover the body and protect both the sterile products and the staff from potential contamination. Because gowns are often manufactured to be worn in a clean environment and allow for limited contamination by their nature, they usually do not need to be changed when leaving the ISO 7 area as long as they remain free of visible contamination during the procedure.

In contrast, shoe covers, face masks, and gloves are items that are more directly involved in preventing the transfer of microorganisms. These items are often used in environments where there is a higher risk of contamination and should be changed frequently to ensure that they do not harbor contaminants upon exiting the sterile area. Therefore, it's the gown that does not require changing when leaving an ISO 7 area, while the other items are typically replaced to maintain a clean protocol.